This paper reports the preliminary findings of an analysis of the Moray House (verbal IQ) results of a base sample of 4383 Orkney children due to be tested in the schools at age 11±1[fraction one-half] years in 1947–75. Girls enjoy a 3·63% premium relative to phenotypically equivalent boys at test age. Relationships within the sample, which includes some members of the parental generation, are known. The trait is found to be X-linked, with nine phenotypes in the boys, and lyonization is (...) involved. (shrink)

While best known for the immensely popular and controversial novel Uncle Tom's Cabin, Harriet Beecher Stowe is also the author of an extensive body of additional work on American culture and politics. Playing many roles--journalist, pamphleteer, novelist, preacher, and advisor on domestic affairs--Stowe used the written word as a vehicle for religious, social, and political commentaries, often leavening them with entertainment in order to reach a broad audience. She had a profound effect on American culture, not because her ideas were (...) unique, but because they were common. What made her so radical was that she insisted on putting her ideas into action. The Oxford Harriet Beecher Stowe Reader offers a focused collection of Stowe's writings from the 1830s through the 1860s. Illustrating her broad range, rhetorical strategies, and cultural designs on the world, it is ideal for courses in nineteenth-century American literature, women's literature, and American history. The volume collects those selections best suited for classroom use, reprinting many pieces here for the first time. Editor Joan D. Hedrick provides a substantial introduction that assesses Stowe's vital impact on nineteenth-century American literature, politics, and culture. The readings are divided into three sections: Early Sketches, Antislavery Writings, and Domestic Culture and Politics. Early Sketches presents the finest writing of Stowe's literary apprenticeship. Antislavery Writings includes Uncle Tom's Cabin in its entirety, placing it in the context of Stowe's considerable and often-overlooked body of other antislavery writings. This section also includes a generous selection from A Key To Uncle Tom's Cabin, a companion volume to the novel. Domestic Culture and Politics shows the scope of Stowe's thinking on the Victorian home, for which she was a major propagandist. The inclusion here of "The True Story of Lady Byron's Life," an exposé of male debauchery and incest at the core of a nineteenth-century home, represents Stowe's willingness to tackle the most challenging political and social issues of her time. (shrink)

The ways in which people conceptualize the human–nature relationship have significant implications for proenvironmental values and attitudes, sustainable behavior, and environmental policy measures. Human exceptionalism (HE) is one such conceptual framework, involving the belief that humans and human societies exist independently of the ecosystems in which they are embedded, promoting a sharp ontological boundary between humans and the rest of the natural world. In this paper, we introduce HE in more depth, exploring the impact of HE on perceptions of the (...) human–nature relationship, the role of culture in HE, and speculating on the origins of HE. We consider potential implications for environmental decision-making, conservation and environmental science, and promoting proenvironmental behavior. We present empirical evidence on the pervasiveness and consequences of HE in WEIRD (Western, Educated, Industrialized, Rich and Democratic) populations, and potential interventions. Finally, we close with implications of human-exceptionalist thinking on other sustainability-related fields, including conservation practices, nature management, climate change adaptation, and environmental science. Understanding the cognitive and social drivers of this disconnect is vital on a planet now dominated by environmental change, as not only are humans increasingly impacted by natural disasters, but the choices they make can have ever more dire consequences for the sustainability of ecosystems. (shrink)

Deep Brain Stimulation is an invasive device-based neuromodulation technique that allows the therapeutic direct stimulation of subcortical and deep cortical structures following the surgical placement of stimulating electrodes. DBS is approved by the U.S. Federal Drug Administration for the treatment of movement disorders and obsessive-compulsive disorder, while new indications, including Major Depressive Disorder, are in experimental development. We report the case of a patient with MDD who received DBS to the ventral internal capsule and ventral striatum bilaterally and presented with (...) 2 weeks of voltage-dependent Tourette-like symptoms including brief transient episodes of abrupt-onset and progressively louder coprolalia and stuttered speech; tic-like motor behavior in his right arm and leg; rushes of anxiety, angry prosody, angry affect; and moderate amnesia without confusion. We describe the results of the inpatient neuropsychiatric workup leading to the diagnosis of iatrogenic voltage-dependent activation of cortico-subcortical circuits and discuss insights into the pathophysiology of Tourette as well as safety considerations raised by the case. (shrink)

NOTES: Based on the book Socrates on trial written by Andrew Irvine and published by the University of Toronto Press. Performed at the Chan Centre for the Performing Arts, University of British Columbia, Vancouver, Canada, May 31-June 7, 2008. CONTENTS: Trailer, Who was Socrates?, Selected scenes, The production, Credits. UBC Library Catalogue Permanent URL: http://resolve.library.ubc.ca/cgi-bin/catsearch?bid=3956307.

We explore the consistency strength of Σ 3 1 and Σ 4 1 absoluteness, for a variety of forcing notions.

Classification of the boys in 48 families of three or more brothers according to their Moray House Test (VIQ) scores awarded at age 11±1[fraction one-half] years in 1947–75 confirms the postulated existence of a total of nine male phenotypes for this X-linked trait in the score range <70 to 140 points. The phenotypic means lie close to the sequence 69(8)133. Recombination is shown to occur. An additive effect of three alleles at each of two X-chromosome loci is the most likely (...) simple scheme. An iterative approach matching the observed mixtures of proposed genotypes in the families with probabilities for variable levels of homozygosity, non-crossover/crossover heterozygosity, and maternal meiotic recombination yields a best goodness of fit where this last is 20%. (shrink)

Book-carrying styles of 1,133 school-age children (kindergarten through high school) were observed, and anatomical measurements (hips, waist, and underarm) of the space between the trunk and fall line of the arm in 735 of the students was recorded. With the exception of handedness, the results replicated those of earlier studies of sexual differences in bookcarrying styles and implicated the protrusion of female hips as instrumental in this phenomenon.

Presents a plethora of approaches to developing human potential in areas not conventionally addressed. Organized in two parts, this international collection of essays provides viable educational alternatives to those currently holding sway in an era of high-stakes accountability.

The everyday harms of structural racism and discrimination, perpetuated through institutions, laws, policies, and practices, constitute social determinants of health, but measures that account for their debilitating effects are largely missing in genetic studies of complex diseases. Drawing on insights from the social sciences and public health, we propose critical methodologies for incorporating tools that measure structural racism and discrimination within genetic analyses. We illustrate how including these measures may strengthen the accuracy and utility of findings for diverse communities, clarify (...) elusive relationships between genetics and environment in a racialized society, and support greater equity within genomics and precision health research. This approach may also support efforts to build and sustain vital partnerships with communities and with other fields of research inquiry, centering community expertise and lived experiences and drawing on valuable knowledge from practitioners in the social sciences and public health to innovate biomedical and genomic study designs aimed at community health priorities. (shrink)

This paper is motivated by the increasing popularity of efficient designs for stated choice experiments. The objective in efficient designs is to create a stated choice experiment that minimizes the standard errors of the estimated parameters. In order to do so, such designs require specifying prior values for the parameters to be estimated. While there is significant literature demonstrating the efficiency improvements of employing efficient designs, the bulk of the literature tests conditions where the priors used to generate the efficient (...) design are assumed to be accurate. However, there is substantially less literature that compares how different design types perform under varying degree of error of the prior. The literature that does exist assumes small fractions are used, which is in contrast to computer-aided surveys that readily allow for large fractions. Further, the results in the literature are abstract in that there is no reference point to provide clear insight on the magnitude of any issue. Our objective is to analyze the robustness of different designs within a typical stated choice experiment context of a trade-off between price and quality. We use as an example transportation mode choice, where the key parameter to estimate is the value of time. Within this context, we test many designs to examine how robust efficient designs are against a misspecification of the prior parameters. The simple mode choice setting allows for insightful visualizations of the designs themselves and also an interpretable reference point for the range in which each design is robust. Not surprisingly, the D-efficient design is most efficient in the region where the true population VOT is near the prior used to generate the design: the prior is $20/h and the efficient range is $10–$30/h. However, the D-efficient design quickly becomes the most inefficient outside of this range, and the estimation significantly degrades above $50/h. The orthogonal and random designs are robust for a much larger range of VOT. The robustness of Bayesian efficient designs varies depending on the variance that the prior assumes. Implementing two-stage designs that first use a small sample to estimate priors are also not robust relative to uninformative designs. Arguably, the random design performs as well as any design, and it will perform even better if data cleaning is done to remove choice tasks where one alternative dominates the other. (shrink)

I raise issues about the scope and content of the religion-and-science field of study and suggest that cultural diversity has not been considered relevant or important. Adding it to the present foci of discussion yields different ideas and constructs about the nature and experience of religion than currently found in most of the religion-and-science literature. Consideration of cultural diversity not only broadens the ideas and constructs but also leads to practical (applied) considerations that have not been prominent in this field.

Background: A high prevalence of cognitive impairment and frailty complicates the feasibility of advance care planning in the long-term-care population. Research aim: To identify challenges in implementing the ‘Let Me Decide’ advance care planning programme in long-term-care. Research design: This feasibility study had two phases: (1) staff education on advance care planning and (2) structured advance care planning by staff with residents and families. Participants and research context: long-term-care residents in two nursing homes and one community hospital. Ethical considerations: The (...) local research ethics committee granted ethical approval. Findings: Following implementation, over 50% of all residents had completed some form of end-of-life care plan. Of the 70 residents who died in the post-implementation period, 14% had no care plan, 10% (with capacity) completed an advance care directive and lacking such capacity, 76% had an end-of-life care plan completed for them by the medical team, following discussions with the resident (if able) and family. The considerable logistical challenge of releasing staff for training triggered development of an e-learning programme to facilitate training. Discussion: The challenges encountered were largely concerned with preserving resident’s autonomy, avoiding harm and suboptimal or crisis decision-making, and ensuring residents were treated fairly through optimisation of finite resources. Conclusions: Although it may be too late for many long-term-care residents to complete their own advance care directive, the ‘ Let Me Decide’ programme includes a feasible and acceptable option for structured end-of-life care planning for residents with variable capacity to complete an advance care directive, involving discussion with the resident (to the extent they were able) and their family. While end-of-life care planning was time-consuming to deliver, nursing staff were willing to overcome this and take ownership of the programme, once the benefits in improved communication and enhanced peace of mind among all parties involved became apparent in practice. (shrink)

En 1994, Sue Rodriguez se suicide avec l’aide d’un médecin après une intense bataille judiciaire en Cour suprême du Canada dont l’objet était la décriminalisation du suicide assisté. À la suite de ce suicide, aucune accusation criminelle ne fut portée contre la ou les personnes ayant présumément aidé Sue Rodrigues à mettre fin à ses jours, et ce malgré le fait que le suicide assisté est un acte criminel au Canada. Cette non-intervention du droit pénal est examinée en fonction du (...) rôle que l’affaire Rodriguez a pu jouer dans la transformation des moralités au Canada. Dans ce livre, le suicide assisté de Sue Rodriguez est envisagé comme un « crime » utile (au sens durkheimien du terme), car il met en évidence une inconsistance entre les moralités dominantes inscrites dans le droit pénal et les conditions sociales qui ont rendu ce « crime » possible. Apparenté au crime de Socrate, le « crime » de Sue Rodriguez est analysé comme un héraut annonciateur de nouvelles moralités, comme un prélude préparant directement la voie à des changements dans le poids accordé aux moralités dominantes. Dans ce contexte, le rôle du droit pénal comme mode privilégié de régulation morale est remis en question. (shrink)

There is little fear that the concept of motivational bias as proposed by Mele is likely to dampen the current academic ferment (see Mele's Introduction) with respect to self-deception for several reasons: (a) like philosophy, science has more recently abandoned the heuristic of a rational human mind; (b) the concept is parsimonious, applicable to many research topics other than self-deception, and, therefore, scientifically serviceable; (c) as a proximal mechanism it addresses process rather than function, that is, how rather than why (...) questions; (d) it is not as interesting a question as why there is a high prevalence of “real” self-deception (i.e., “garden-variety self-deception” as described by Mele, see sect. 6); and (e) a more penetrating issue is whether “real” self-deception is adaptive. (shrink)

E l auto r pa r t e de l reconocimient o d e qu e lo s parámetro s e n lo s qu e s e inscribía n las institucione s d e l a democraci a representat iva ha n cambiad o sustancialmente . E n es e nu evo cont e xt o sitú a e l debat e sobr e lo s posi b le s dé f icit s d e l a democraci a (...) representat iva y espe- cí f icament e e l crecient e desapoderamient o d e l a capacida d popula r d e influi r y condicionar la s decisiones , qu e hac e perde r l e gitimida d a un a democraci a qu e sól o mantien e abie r tas la s pue r ta s d e lo s rito s fo r male s e institucionales . E n s e gund o luga r , e l a r tícul o s e centra e n lo s efecto s qu e tien e l a generalizació n d e inte r ne t e n es e escenario . E l auto r constata cóm o la s estrat e gia s d e us o d e la s TI C hast a ahor a desa r rollada s e n e l espaci o polític o se ha n centrad o e n l a mejor a d e l a capacida d d e prestació n d e se r vicio s o e n l a ampliació n de l a capacida d d e elecció n d e lo s consumidores-ciudadanos , per o n o e xist e un a v olunta d d e ir má s all á d e un a concepció n d e l a democraci a qu e s e centr a e n la s r e gla s procedimentales y e n un a visió n mu y estrict a de l principi o d e representación . F rent e a esta s estrat e gias, e l a r tícul o aborda , po r u n lado , la s relacione s entr e Inte r net , m o vimiento s sociale s y las nu ev a s fo r ma s d e hace r polític a (centrándos e e n l a e xperienci a de l 15M ) y , po r otr o lado , la posibilida d d e repensa r d e nu evo e l viej o tem a d e l a democraci a direct a y l a pa r ticipación ciudadan a qu e l a e xtensió n y generalizació n d e Inte r ne t pe r miten . E n amba s estrat e gia s late l a preocupació n po r l a calida d d e l a pa r ticipació n y l a capacida d d e implicació n d e l a gente e n lo s asunto s colect iv o s tant o a n i v e l polític o com o ví a necesari a n o sól o par a defender su s intereses , sin o com o fo r m a d e entende r l a democracia , un a democraci a relaciona l y pa r ticipat iv a. (shrink)

When (if ever) may a professional deceive a client for the client's own good? Under what conditions (if any) is whistle-blowing morally required? These are just some of the questions that scholars as diverse as Michael D. Bayles, Thomas Nagel, Sissela Bok, Jessica Mitford, and Peter A. French confront in this stimulating anthology. Organized around philosophical issues such as the moral foundations of professional ethics, models of the professional-client relationship, deception, informed consent, privacy and confidentiality, professional dissent, and professional virtue, (...) the volume illuminates the complex ethical issues that arise in journalism, law, health care, counselling, education, engineering, business, politics, and social science research. A variety of pedagogical aids--including clear introductions to and study questions for each set of readings, concrete cases designed to focus discussion, and an appendix on preparing cases and position papers--makes the text invaluable for both students and teachers of professional ethics. (shrink)